Atopic dermatitis: Current standards of diagnosis and treatment, including the latest methods of management

Abstract Atopic dermatitis (AD) is a chronic relapsing disease which causes characteristic eczematous skin lesions. The most common symptoms of atopic are persistent pruritus, xerosis, and lesions with typical location appearance that changes the patient’s age. prevalence in pediatric population estimated at 10% to 30%, while adults it ranges from 1% 3%. number people who suffer AD rising every year. pathophysiology complex multifactorial. It involves elements epidermal barrier dysfunction, alterations cellular immune response, IgE hypersensitivity, environmental factors. significantly reduces quality life both patients their families. Patients higher risk for neuropsychiatric disorders such as depression, attention-deficit/hyperactivity disorder, headaches. decreased families associated discomfort recurrent inflammatory lesions, inconvenience long-term therapy. also affects psychological development children, contributes behavioral (hyperactivity, hypersensitivity) impacts many areas family sleep, leisure activities, relationships between members. basic treatment avoidance potential harmful factors, proper care exacerbations, topical corticosteroids, calcineurin inhibitors proactive In some meet age criteria, phototherapy cyclosporine should be considered. individuals severe do not respond will benefit general therapy, dupilumab, biologic drug, choice. Biologic has an increasingly important place effective modern therapy AD. Currently, new drugs being researched, may bring therapeutic revolution future. Allergen immunotherapy carefully evaluated on individual basis, selection documented IgE-dependent sensitization success this Close collaboration patient caregivers, education, support appropriate integral treatment.